# Poison Poison is an ailment that deals chaos damage over time to the affected target.[1] ## Mechanics A hit of damage that has a chance to poison is capable of inflicting poison. Only physical and chaos damage are able to inflict poison.[2] Poison is a cumulatively stacking debuff. Each application—or 'stack'—of poison remains present on the target dealing chaos damage over time until it runs its course.[2] There is no limit to the number of poison stacks a target can have.[1] A single "hit" can apply a maximum of one poison stack, therefore having more than 100% chance to poison is redundant.[3] ### Damage The base damage per second dealt by a given application of poison equals 30% of the combined physical and chaos damage of the base damage dealt which applied that particular instance of poison.[4] As an ailment modifier, stats modifying spell damage and attack damage do not apply to poison, nor damage modifers that are only affected by the skill. The following modifiers will directly affect the damage of poison: - Damage - Damage over Time - Damage over Time Multiplier - Chaos Damage over Time Multiplier - Chaos Damage - Poison Damage - Physical Damage (for poison caused by physical damage)[5] because the poison DOT is based on and scaled by the value of the physical and chaos damage of the hit that inflicts the poison ailment Minion, trap, mine or totem damage modifiers will also affect the damage of poison if it is applied by a minion, a trap, a mine, or a totem respectively.[6][better source needed] ### Duration The default base duration of poison is 2 seconds. [[Viper Strike]] inflicts poison with a base duration of 4 seconds. Increasing poison duration results in a longer-lasting poison that deals damage at the same rate [citation needed]. increased Poison Duration, increased Duration of Ailments on Enemies and [[Temporal Chains]] are means to increase the duration of poisons on enemies. Removal, immunity, and unaffected by - A flask with the of Curing suffix removes poison on sip and grants immunity to it while active - [[Viper's Scales]] grants immunity to poison - Boots crafted with [[Essence of Delirium]] grant immunity to poison - [[Maw of Conquest]] has the modifier "Unaffected by Poison" meaning poison can still be inflicted upon the character, but the character will not take damage from it